My grandma was a saint. I don't make that claim because she gave me cookies or was a foster parent or any of the other awesome things she did. She was a saint because of what she didn't do. She didn't throw out her son's baseball cards!
Because of that, as a kid, I always looked forward to the 2 hour drive to grandma's so I could see 'old' baseball cards. She had a few hundred cards from the very late 50's to the mid 60's. I remember a 62 Willie Mays and a cereal box cutout card of Sandy Koufax, but most were just junk. I think my uncles got ripped off a lot!
The card I remember most and always have looked for is a 1964 Topps Rusty Staub. This card was my introduction to the Houston Colt 45's, precursor to the Astros. It was also awesome in my mind because of the HUGE rookie cup! I didn't find out until years later that it wasn't even his RC.